Methylamine → HCID 178482580, compound

Participants

Reaction Steps

To 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde 10 (1.0 g) in methanol under nitrogen was added methylamine solution (11.79 g methylamine in 50 ml methanol) (1.39 ml). The reaction mixture was stirred at room temperature overnight. The solvents were then removed in vacuo to yield [1-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-yl)-meth-(E)-ylidene]-methyl-amine.

Provenance & Evidence