HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylsulfonylaminophenylboronic acid → HCID 59593051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylsulfonylaminophenylboronic acid | HCID 2773535 | — |
| Reactant | 2-(1H-indazol-4-yl)-4-morpholinothieno[2,3-d]pyrimidine-6-carboxylic acid | HCID 59592885 | — |
| Product | HCID 59593051 | HCID 59593051 | — |
Reaction Steps
2-Chloro-6-iodo-4-morpholinofuro[3,2-d]pyrimidine 45 from Example 27 was reacted with 3-(methylsulfonylamino)phenylboronic acid via General Procedure A to give the corresponding intermediate, after purification by flash chromatography, which was then reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 7 to give, after purification by reverse phase HPLC, 327. MS (Q1) 491 (M+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846929B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-01eded95d4e8471e98595d31ceb48413 |
| Source note | uspto-grants-2010_12 |