HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dimethoxyethane → HCID 57668739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dimethoxyethane | HCID 8071 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromo-4-methylpyridine | HCID 2734087 | — |
| Reactant | (3-Phenylphenyl)boronic acid | HCID 2734315 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 57668739 | HCID 57668739 | — |
Reaction Steps
9.0 g (0.05 mol) of 2-bromo-4-methylpyridine, 12.0 g (0.06 mol) of 3-biphenylboronic acid, 1.7 g (0.0015 mol) of Pd(Ph3)4, 19.0 g (0.135 mol) of K2CO3, 50 mL of DME and 50 mL of water. The reaction mixture was refluxed for 20 hours and separated on silica gel column. MS confirmed the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851072B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-f037160cca6f4f488ffb589a422e5f1d |
| Source note | uspto-grants-2010_12 |