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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262533Generated: November 2, 2026

4-Fluorobenzonitrile → HCID 25130782, compound

https://huagongshe.com/reaction/2262533

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzonitrileHCID 14517—
ReactantHCID 178506308HCID 178506308—
ProductHCID 25130782HCID 2513078249%

Reaction Steps

As described for Example 4, 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole (90 mg, 0.32 mmol) was converted, using 4-fluorobenzonitrile instead of 4-fluorobenzotrifluoride, to the title compound (60 mg, 49%) which was obtained as a white solid. MS: m/e=381.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-1cdc7e7f18c24be5b542e016d6f01e13
Source noteuspto-grants-2010_12