HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 25131103, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 25130783 | HCID 25130783 | — |
| Product | HCID 25131103 | HCID 25131103 | 40% |
Reaction Steps
As described for Example 10, 4-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid methyl ester (70 mg, 0.17 mmol) was converted, using morpholine instead of cyclopropanemethylamine, to the title compound (32 mg, 40%) which was obtained as a white foam. MS: m/e=469.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-67055d57d64f493dbce9495681b24e6e |
| Source note | uspto-grants-2010_12 |