HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-5-(trifluoromethyl)pyridine → HCID 25132123, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-5-(trifluoromethyl)pyridine | HCID 5463754 | — |
| Reactant | HCID 178506308 | HCID 178506308 | — |
| Product | HCID 25132123 | HCID 25132123 | 79% |
Reaction Steps
As described for Example 4, 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole (100 mg, 0.36 mmol) was converted, using 2-fluoro-5-(trifluoromethyl)pyridine instead of 4-fluorobenzotrifluoride, to the title compound (120 mg, 79%) which was obtained as a white solid. MS: m/e=425.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-d932782939fe46be8bbc065768848ecc |
| Source note | uspto-grants-2010_12 |