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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262547Generated: November 3, 2026

Cyclopropylamine → HCID 25132480, compound

https://huagongshe.com/reaction/2262547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantHCID 25132124HCID 25132124—
ProductHCID 25132480HCID 2513248052%

Reaction Steps

As described for Example 18, 6-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-nicotinic acid methyl ester (90 mg, 0.22 mmol), was converted, using cyclopropylamine instead of cyclopropanemethylamine, to the title compound (50 mg, 52%) which was obtained as a white solid. MS: m/e=440.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-04f12deeda3e40b9aae14e7d0e5cf159
Source noteuspto-grants-2010_12