HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiomorpholine → HCID 25132818, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiomorpholine | HCID 67164 | — |
| Reactant | HCID 25132124 | HCID 25132124 | — |
| Product | HCID 25132818 | HCID 25132818 | 51% |
Reaction Steps
As described for Example 18, 6-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-nicotinic acid methyl ester (70 mg, 0.17 mmol), was converted, using thiomorpholine instead of cyclopropanemethylamine, to the title compound (42 mg, 51%) which was obtained as a colourless oil. MS: m/e=486.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-6c3b9dcf04b64a548f2adc979eae0cc7 |
| Source note | uspto-grants-2010_12 |