5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole → 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1,2-oxazole

関与物質

反応手順

As described for Example 1b, 3-(4-fluoro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-5-ol (35.6 g, 142.9 mmol), instead of 3-phenyl-5-hydroxy-5-(trifluoromethyl)isoxazoline, was converted to the title compound (32.2 g, 98%) which was obtained as a light brown solid. MS: m/e=298.1 [M+H]+.

情報源と証拠