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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2262553Erstellt: 25. Oktober 2026

3-(4-Fluorophenyl)-5-(trifluoromethyl)-1,2-oxazole → 1-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-isoxazol-4-yl]-ethanone

https://huagongshe.com/reaction/2262553

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(4-Fluorophenyl)-5-(trifluoromethyl)-1,2-oxazoleHCID 799214—
Edukt3-phenyl-4-(1-phenyl-1H-imidazol-4-yl)-5-trifluoromethyl-isoxazoleHCID 25130449—
Produkt1-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-isoxazol-4-yl]-ethanoneHCID 6736270285%

Reaktionsschritte

As described for Example 1e, 3-(4-fluoro-phenyl)-5-trifluoromethyl-isoxazole (50.0 mg, 216 mmol), instead of 3-phenyl-4-(1-phenyl-1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole, was converted to the title compound (50.2 mg, 85%) which was obtained as a light yellow oil. MS: m/e=272.1 [M−H]−.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07851469B2
Quelldatensatzuspto-grants-2010_12
ORD IDord-36fcfed1ec024723b6f4c3abdf956651
Quellennotizuspto-grants-2010_12