HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzonitrile → HCID 25131430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzonitrile | HCID 14517 | — |
| Reactant | HCID 178505600 | HCID 178505600 | — |
| Product | HCID 25131430 | HCID 25131430 | 67% |
Reaction Steps
As described for Example 24, 3-(4-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (100 mg, 0.34 mmol), using 4-fluorobenzonitrile instead of 4-fluoroacetophenone, was converted to the title compound (90 mg, 67%) which was obtained as a white solid. MS: m/e=399.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-8faa5f38fd9348f99f36e3e12bbba174 |
| Source note | uspto-grants-2010_12 |