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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262557Generated: November 4, 2026

Methyl 4-fluorobenzoate → HCID 25131431, compound

https://huagongshe.com/reaction/2262557

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-fluorobenzoateHCID 67878—
ReactantHCID 178505600HCID 178505600—
ProductHCID 25131431HCID 2513143144%

Reaction Steps

As described for Example 24, 3-(4-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (900 mg, 3.0 mmol), using methyl 4-fluorobenzoate instead of 4-fluoroacetophenone, was converted to the title compound (580 mg, 44%) which was obtained as a white solid. MS: m/e=432.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-a4eb03a67b83406ca8e55b976f5d5e80
Source noteuspto-grants-2010_12