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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262565Generated: November 2, 2026

1-(6-Chloropyridin-3-yl)ethan-1-one → HCID 25132819, compound

https://huagongshe.com/reaction/2262565

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Chloropyridin-3-yl)ethan-1-oneHCID 2779698—
ReactantHCID 178505600HCID 178505600—
ProductHCID 25132819HCID 2513281938%

Reaction Steps

As described for Example 24, 3-(4-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (120 mg, 0.4 mmol), using 1-(6-chloro-3-pyridinyl)-1-ethanone instead of 4-fluoroacetophenone, was converted to the title compound (64 mg, 38%) which was obtained as a light yellow solid. MS: m/e=417.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-98516bb1387f4ecd911d869ca94b8a64
Source noteuspto-grants-2010_12