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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262567Generated: November 3, 2026

Methyl 6-chloropyridine-3-carboxylate → HCID 67363061, compound

https://huagongshe.com/reaction/2262567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 6-chloropyridine-3-carboxylateHCID 254249—
ReactantHCID 178505600HCID 178505600—
ProductHCID 67363061HCID 6736306171%

Reaction Steps

As described for Example 4, 3-(4-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (700 mg, 2.4 mmol) instead of 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole was converted, using methyl 6-chloronicotinate instead of 4-fluorobenzotrifluoride, to the title compound (720 mg, 71%) which was obtained as a white solid. MS: m/e=433.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-e8b8be7c801f41cea34ee7b10e257b72
Source noteuspto-grants-2010_12