HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-fluoro-4-(trifluoromethyl)- → HCID 25132120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-fluoro-4-(trifluoromethyl)- | HCID 67873 | — |
| Reactant | HCID 178506309 | HCID 178506309 | — |
| Product | HCID 25132120 | HCID 25132120 | 34% |
Reaction Steps
As described for Example 44, 3-(4-chloro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (100 mg, 0.32 mmol), using 4-fluorobenzotrifluoride instead of 4-fluoroacetophenone, was converted to the title compound (50 mg, 34%) which was obtained as a white solid. MS: m/e=458.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-3a887f575bb14322b5a7ff49f1d939c4 |
| Source note | uspto-grants-2010_12 |