Methyl 6-chloropyridine-3-carboxylate → HCID 67361949, compound

Participants

Reaction Steps

As described for Example 4, 3-(4-chloro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (700 mg, 2.2 mmol) instead of 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole was converted, using methyl 6-chloronicotinate instead of 4-fluorobenzotrifluoride, to the title compound (750 mg, 75%) which was obtained as a white solid. MS: m/e=449.0 [M+H]+.

Provenance & Evidence