HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 6-chloropyridine-3-carboxylate → HCID 67362846, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 6-chloropyridine-3-carboxylate | HCID 254249 | — |
| Reactant | HCID 178505666 | HCID 178505666 | — |
| Product | HCID 67362846 | HCID 67362846 | 68% |
Reaction Steps
As described for Example 4, 3-(3-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (500 mg, 1.68 mmol) instead of 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole was converted, using methyl 6-chloronicotinate instead of 4-fluorobenzotrifluoride, to the title compound (495 mg, 68%) which was obtained as a white solid. MS: m/e=433.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-a7ca9b3bd0ee42cea2119bbd6f575bcd |
| Source note | uspto-grants-2010_12 |