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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262586Generated: November 3, 2026

Methyl 6-chloropyridine-3-carboxylate → HCID 67362846, compound

https://huagongshe.com/reaction/2262586

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 6-chloropyridine-3-carboxylateHCID 254249—
ReactantHCID 178505666HCID 178505666—
ProductHCID 67362846HCID 6736284668%

Reaction Steps

As described for Example 4, 3-(3-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-trifluoromethyl-isoxazole (500 mg, 1.68 mmol) instead of 4-(1H-imidazol-4-yl)-3-phenyl-5-trifluoromethyl-isoxazole was converted, using methyl 6-chloronicotinate instead of 4-fluorobenzotrifluoride, to the title compound (495 mg, 68%) which was obtained as a white solid. MS: m/e=433.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-a7ca9b3bd0ee42cea2119bbd6f575bcd
Source noteuspto-grants-2010_12