HCID 68686109, compound → HCID 68684908, compound

Participants

Reaction Steps

To a solution of 2-[5-(4-methyl-piperazin-1-yl)-2-nitro-phenyl]-acetamide (468 mg, 1.68 mmol) in MeOH (8.0 mL) is added 10% Pd on charcoal (59 mg). The reaction mixture is stirred for 18 h under a hydrogen atmosphere (1 atm.), filtered through a microfilter (0.45 μM), and the filtrate concentrated at reduced pressure. The remaining brown oil is dissolved in MeOH (1 mL), MTBE (5 mL) is added, and the solvent is carefully removed at reduced pressure to afford the title compound as a beige powder. ES+-MS: 249 [M+H]+.

Provenance & Evidence