HCID 16064536, compound → HCID 57442579, compound

HRID 2262709Notes

Reaction equation

HRID 2262709 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]([N:19]3[CH2:24][CH2:23][N:22]([CH:25]4[CH2:29][CH2:28][CH2:27]C4)[CH2:21][CH2:20]3)=[O:18])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)(=[O:3])[CH3:2].ClCC(N1CCN(C2CCC2)CC1)=[O:33]>>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]([N:19]3[CH2:20][CH2:21][N:22]([CH:25]4[CH2:27][CH2:28][CH2:29]4)[CH2:23][CH2:24]3)=[O:18])[CH2:12][C:11]2=[O:33])=[CH:8][CH:9]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 16064536HCID 16064536, compoundHCID 574205621-(Chloroacetyl)-4-cyclobutylpiperazine

Product 1

HCID 57442579HCID 57442579, compound

Procedure

The intermediate obtained from step 2 is reacted with 1-(chloroacetyl)-4-cyclobutylpiperazine as in Example 1D, step 3 to give the title compound. LC-MS (M+1): 399.21.

Sources & evidence

ORD record
ord-d18448f31b8d4b4ba670c2cee3f1475c
Source dataset
uspto-grants-2010_12
Patent number
US07851474B2

Reaction notes

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