Triethylamine hydrochloride → HCID 178521864, compound

Participants

Reaction Steps

N-[3-cyano-biphenyl-4-yl]-3,5-bis-trifluoromethyl-benzamide (100 mg), sodium azide (40 mg) and triethylamine hydrochloride (103 mg) were stirred at 100° C. for 20 hours in DMF (3 ml). The reaction mixture was poured into a 5% KHSO4 solution (10 ml) and the solid was filtered off and dried to give N-[3-(1H-Tetrazol-5-yl)-biphenyl-4-yl]-3,5-bis-trifluoromethyl-benzamide as a white solid (120 mg). Mp.=156° C. (dec.).

Provenance & Evidence