HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → HCID 68965045, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | HCID 10752245 | HCID 10752245 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68965045 | HCID 68965045 | 65.5% |
Reaction Steps
A mixture of methyl 6-(4-piperidylamino)nicotinate (0.73 g) and phenyl isocyanate (388 mg) in THF (30 ml) was stirred at ambient temperature for 12 hours. IPE (30 ml) was added to a reaction mixture and the precipitate was collected by filtration to give methyl 6-{[1-(anilinocarbonyl)-4-piperidyl]amino}nicotinate (0.72 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557127B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-54000c3c108d46f2bf4eec7e7cfc90c7 |
| Source note | uspto-grants-2009_07 |