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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226310Generated: October 30, 2026

Phenyl isocyanate → HCID 68965045, compound

https://huagongshe.com/reaction/226310

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl isocyanateHCID 7672—
ReactantHCID 10752245HCID 10752245—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68965045HCID 6896504565.5%

Reaction Steps

A mixture of methyl 6-(4-piperidylamino)nicotinate (0.73 g) and phenyl isocyanate (388 mg) in THF (30 ml) was stirred at ambient temperature for 12 hours. IPE (30 ml) was added to a reaction mixture and the precipitate was collected by filtration to give methyl 6-{[1-(anilinocarbonyl)-4-piperidyl]amino}nicotinate (0.72 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557127B2
Source datasetuspto-grants-2009_07
ORD IDord-54000c3c108d46f2bf4eec7e7cfc90c7
Source noteuspto-grants-2009_07