3-Methylacetophenone → 2-Bromo-1-(3-methylphenyl)ethan-1-one

Participants

Reaction Steps

Bromine (2.38 g, 14.9 mmol) was slowly added dropwise to a solution of 1-[3-methylphenyl]ethanone (2.00 g, 14.9 mmol) in diethyl ether (50 ml), and the mixture was stirred at room temperature for 4 hours. The reaction mixture was distilled off under reduced pressure to give 3.03 g (95.3%) of the desired product as an oil.

Provenance & Evidence