Bromine → 2-Bromo-1-(2,3-dichlorophenyl)ethan-1-one

HRID 2263317Notes

Reaction equation

HRID 2263317 reaction equation
[Br:1]Br.[Cl:3][C:4]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:5]=1[C:11](=[O:13])[CH3:12]>C(OCC)C>[Br:1][CH2:12][C:11]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:4]=1[Cl:3])=[O:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 919861-(2,3-Dichlorophenyl)ethan-1-one

Product 1

HCID 126224802-Bromo-1-(2,3-dichlorophenyl)ethan-1-one

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Bromine (2.54 g, 15.9 mmol) was slowly added dropwise to a solution of 1-(2,3-dichlorophenyl)ethanone (3.00 g, 15.9 mmol) in diethyl ether (60 ml), and the mixture was stirred at room temperature for 4 hours. The reaction mixture was distilled off under reduced pressure to give 2-bromo-1-(2,3-dichlorophenyl)ethanone as an oil quantitatively.

Workup

  1. distillationThe reaction mixture was distilled off under reduced pressure

Sources & evidence

ORD record
ord-1788429c748a437ebed6f0c2acd418b8
Source dataset
uspto-grants-2010_12
Patent number
US07851473B2

Reaction notes

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