Water → 2-(2,4-Dichlorophenyl)-2-oxoethyl thiocyanate

HRID 2263325Notes

Reaction equation

HRID 2263325 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:6]=1[Cl:12])=[O:4].[S-:13][C:14]#[N:15].[K+].O>C(O)C>[Cl:12][C:6]1[CH:7]=[C:8]([Cl:11])[CH:9]=[CH:10][C:5]=1[C:3](=[O:4])[CH2:2][S:13][C:14]#[N:15]

Participants

5

Reactant 3

HCID 962WaterHCID 758282-Bromo-1-(2,4-dichlorophenyl)ethan-1-oneHCID 516872Potassium thiocyanate

Product 1

HCID 143976042-(2,4-Dichlorophenyl)-2-oxoethyl thiocyanateYield 91.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 2-bromo-1-(2,4-dichlorophenyl)ethanone (7.09 g, 26.5 mmol) and potassium thiocyanate (2.57 g, 26.5 mmol) in ethanol (70 ml) was stirred at 80° C. for 2 hours. After cooling to room temperature, water (70 ml) was poured to the reaction mixture, and crystals were collected by filtration and washed with water to give 5.97 g (91.7%) of the desired product as a solid.

Workup

  1. filtrationwere collected by filtration
  2. washwashed with water

Sources & evidence

ORD record
ord-0424cf90c9764346a6160c8242f852e1
Source dataset
uspto-grants-2010_12
Patent number
US07851473B2

Reaction notes

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