HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → tert-Butyl 2-(3-cyanophenyl)-3-propylcarbazate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Tert-butyl 2-(3-cyanophenyl)-3-propyl-3-(2,2,2-trifluoracetyl)carbazate | HCID 22591513 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-Butyl 2-(3-cyanophenyl)-3-propylcarbazate | HCID 22591495 | 63.8% |
Reaction Steps
5.64 g (15.187 mmol) of crude product 403 are dissolved in 100 ml of methanol and treated at RT with 10 ml of completely deionized water and 1.08 g (45.24 mmol) of lithium hydroxide. The reaction mixture is then stirred for 5 h. After customary work-up, 2.67 g (63.8%) of 404 are thus obtained as an oil; MS(FAB)=276.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849626B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-f82342c37f134165b376c8e3ea59ff61 |
| Source note | uspto-grants-2005_02 |