HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 57883931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Methyl 4-(aminomethyl)benzoate | HCID 571728 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1,1-Dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea | HCID 57883471 | — |
| Product | HCID 57883931 | HCID 57883931 | 36.4% |
Reaction Steps
Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (150 mg. 0.42 mmol), acetic acid (24 μL, 0.42 mmol), 4-aminomethyl-benzoic acid methyl ester (170 mg, 0.84 mmol) and sodium triacetoxyborohydride (268 mg, 1.27 mmol) to afford 74 mg (36%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851636B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-22174a6fdfe54bc0b247d6f1491e1df8 |
| Source note | uspto-grants-2010_12 |