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HRID2263893

反应详情

EQUATION

反应方程式

HRID 2263893 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@@H]1CNCCN1C
HCID29920832

Methyl (2S)-1-methyl-2-piperazinecarboxylate

C7H14N2O2

结构：CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl
HCID58894207

rel-(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazole-1-carbonyl chloride

C30H31Cl3N2O2

PRODUCTS

生成物

1
结构：CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C)[C@H](C(=O)OC)C1
HCID17754847

未命名化合物

PROCEDURE

实验过程

In a manner analogous to the method described in example 5, (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 4) was reacted with (S)-1-methyl-piperazine-2-carboxylic acid methyl ester (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C37H45N4O4Cl2 [(M+H)+] 679.2813, observed 679.2805.