Phosgene → rac-(4S*,5R*)-2-(5-tert-Butylsulfamoyl-4-chloro-2-ethoxyphenyl)-4,5-bis-(4-chlorophenyl)-4,5-dimethyl-4,5-dihydroimidazole-1-carbonyl chloride

Participants

Reaction Steps

In a manner analogous to the method described in example 3, rac-(4S*,5R*)-5-[4,5-bis-(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-2-yl]-N-tert-butyl-2-chloro-4-ethoxybenzene-sulfonamide (example 44) was reacted with phosgene in the presence of triethylamine to give the title compound.

Provenance & Evidence