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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2263989Generated: October 30, 2026

4-Cyanobenzoyl chloride → HCID 17754259, compound

https://huagongshe.com/reaction/2263989

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Cyanobenzoyl chlorideHCID 80172—
Reactantrac-(4S*,5R*)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazoleHCID 53628801—
ProductHCID 17754259HCID 17754259—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole was reacted with 4-cyano-benzoyl chloride (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C37H36N3O2Cl2 [(M+H)+] 624.2179, observed 624.2177.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-ff8bb654b49047ad959ec383c5b5eef7
Source noteuspto-grants-2010_12