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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2263998Generated: October 31, 2026

Piperazin-2-one → HCID 17754405, compound

https://huagongshe.com/reaction/2263998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazin-2-oneHCID 231360—
Reactantrac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408688—
ProductHCID 17754405HCID 17754405—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 2-piperazinone (Avocado Organics) to give the title compound. HR-MS (ES, m/z) calculated for C31H30N4O3F3Cl2 [(M+H)+] 633.1642, observed 633.1638.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-dc4c1da8258c48fc9c7647a483eb1bb6
Source noteuspto-grants-2010_12