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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264001Generated: November 2, 2026

1-(Morpholinocarbonylmethyl)piperazine → HCID 58894254, compound

https://huagongshe.com/reaction/2264001

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Morpholinocarbonylmethyl)piperazineHCID 100622—
Reactantrac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408688—
ProductHCID 58894254HCID 58894254—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 1-morpholin-4-yl-2-piperazin-1-yl-ethanone (Oakwood Products) to give the title compound. HR-MS (ES, m/z) calculated for C37H41N5O4F3Cl2 [(M+H)+] 746.2482, observed 746.2483.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-115fe4222d144ad5b25218e267482889
Source noteuspto-grants-2010_12