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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264004Generated: October 30, 2026

4-Morpholinopiperidine → HCID 58894244, compound

https://huagongshe.com/reaction/2264004

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MorpholinopiperidineHCID 795724—
Reactantrac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408688—
ProductHCID 58894244HCID 58894244—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 4-piperidin-4-yl-morpholine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C36H40N4O3F3Cl2 [(M+H)+] 703.2424, observed 703.2419.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-48f345201be34d45bba3a7f16b85bebf
Source noteuspto-grants-2010_12