HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidin-4-ol → HCID 58894255, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidin-4-ol | HCID 79341 | — |
| Reactant | rac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 73408688 | — |
| Product | HCID 58894255 | HCID 58894255 | — |
Reaction Steps
In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 4-hydroxy-piperidine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C32H33N3O3F3Cl2 [(M+H)+] 634.1846, observed 634.1846.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851626B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-9756b3062fff4f47a5ed39c575591674 |
| Source note | uspto-grants-2010_12 |