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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264006Generated: October 30, 2026

4-Piperidinemethanol → HCID 58894219, compound

https://huagongshe.com/reaction/2264006

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidinemethanolHCID 420771—
Reactantrac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408688—
ProductHCID 58894219HCID 58894219—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with piperidin-4-yl-methanol (Lancaster) to give the title compound. HR-MS (ES, m/z) calculated for C33H35N43O3F3Cl2 [(M+H)+] 648.2002, observed 648.2006.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-86a9bcf2cbe5464ab8bf8d3a7430ee13
Source noteuspto-grants-2010_12