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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264007Generated: October 30, 2026

4-Piperidinecarboxamide → HCID 58894296, compound

https://huagongshe.com/reaction/2264007

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidinecarboxamideHCID 3772—
Reactantrac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408688—
ProductHCID 58894296HCID 58894296—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with piperidine-4-carboxylic acid amide (isonipecotamide, Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C33H34N4O3F3Cl2 [(M+H)+] 661.1955, observed 662.1955.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-80abee500541439f9631041a9725aca7
Source noteuspto-grants-2010_12