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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264018Generated: October 26, 2026

1-Isopropylpiperazine → HCID 58894260, compound

https://huagongshe.com/reaction/2264018

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IsopropylpiperazineHCID 78013—
Reactantrac-(4S*,5R*)-2-(4-tert-Butyl-2-isopropoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 72455766—
ProductHCID 58894260HCID 58894260—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-2-(4-tert-butyl-2-isopropoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 1-isopropyl-piperazine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C38H49N4O2Cl2 [(M+H)+] 663.3227, observed 663.3228.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-edfdd2fbe74d4d48b25d1448c71f76c5
Source noteuspto-grants-2010_12