HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-1,4-Diazabicyclo[4.4.0]decane → HCID 58894310, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-1,4-Diazabicyclo[4.4.0]decane | HCID 2876391 | — |
| Reactant | rac-(4S*,5R*)-2-(4-tert-Butyl-2-isopropoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 72455766 | — |
| Product | HCID 58894310 | HCID 58894310 | — |
Reaction Steps
In a manner analogous to the method described in example 5, rac-(4S*,5R*)-2-(4-tert-butyl-2-isopropoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with octahydro-pyrido[1,2-a]pyrazine (Aldrich) to give the title compound as a mixture of diastereomers. HR-MS (ES, m/z) calculated for C39H49N4O2Cl2 [(M+H)+] 675.3227, observed 675.3224.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851626B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-c6d53c4d77d34d3384bd84218ec971cd |
| Source note | uspto-grants-2010_12 |