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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264062Generated: November 1, 2026

1-((Pyrrolidine-1-carbonyl)methyl)piperazine → HCID 58894295, compound

https://huagongshe.com/reaction/2264062

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((Pyrrolidine-1-carbonyl)methyl)piperazineHCID 100614—
Reactantrac-(4S*,5R*)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4-methyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 72455720—
ProductHCID 58894295HCID 58894295—

Reaction Steps

In a manner analogous to the method described in example 5, rac-(4S*,5R*)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4-methyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 2-piperazin-1-yl-1-pyrrolidin-1-yl-ethanone (Aldrich) to give the title compound. LC-MS: 704.3 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851626B2
Source datasetuspto-grants-2010_12
ORD IDord-d84068a1dae24bb7a6a2f7fe92013a42
Source noteuspto-grants-2010_12