3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → HCID 59595982, compound

HRID 2264180Notes

Reaction equation

HRID 2264180 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][C:10]=2[Cl:15])O1.[Cl:17][C:18]1[N:23]=[C:22]([NH2:24])[C:21]([N+:25]([O-:27])=[O:26])=[CH:20][C:19]=1I>>[Cl:17][C:18]1[C:19]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][C:10]=2[Cl:15])=[CH:20][C:21]([N+:25]([O-:27])=[O:26])=[C:22]([NH2:24])[N:23]=1

Participants

3

Reactant 2

HCID 447551543-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 59596003HCID 59596003, compound

Product 1

HCID 59595982HCID 59595982, compoundYield 22%

Procedure

Following the same procedure as in Intermediate 1 (step a), but using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloropyridine, 6-chloro-5-iodo-3-nitropyridin-2-amine (Intermediate 5—step a) was transformed into the title compound as a white solid (205 mg, 22%).

Sources & evidence

ORD record
ord-74ff73565219489da593bc5512d8950f
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

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