4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → HCID 59596004, compound

HRID 2264185Notes

Reaction equation

HRID 2264185 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)O1.Br[C:17]1[C:18]([C:27]2[CH:32]=[CH:31][N:30]=[CH:29][C:28]=2[Cl:33])=[N:19][C:20]([NH2:26])=[C:21]([N+:23]([O-:25])=[O:24])[CH:22]=1>>[Cl:33][C:28]1[CH:29]=[N:30][CH:31]=[CH:32][C:27]=1[C:18]1[C:17]([C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)=[CH:22][C:21]([N+:23]([O-:25])=[O:24])=[C:20]([NH2:26])[N:19]=1

Participants

3

Reactant 2

HCID 27346484-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 59595999HCID 59595999, compound

Product 1

HCID 59596004HCID 59596004, compoundYield 85%

Procedure

Following the same procedure as in Intermediate 1 (step a), but using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 3-bromo-3′-chloro-5-nitro-2,4′-bipyridin-6-amine was converted to the title compound as yellowish solid (0.84 g, 85%).

Sources & evidence

ORD record
ord-342cf033294b4167847790ffdc3717d1
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

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