HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68966904, compound → HCID 86603725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68966904 | HCID 68966904 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86603725 | HCID 86603725 | 90.9% |
Reaction Steps
A mixture of {2-[(1-benzyl-3-pyrrolidinyl)amino]-4-methyl-5-pyrimidinyl}methanol (1.75 g) and MnO2 (5.1 g) in AcOEt (30 ml) was refluxed under stirring for 1.5 hours. After removal of the insoluble material, and the solvent was evaporated in vacuo to give 2-[(1-benzyl-3-pyrrolidinyl)amino]-4-methyl-5-pyrimidinecarbaldehyde (1.58 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557127B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-ebf20a60e7df4330a84f20419eb19aec |
| Source note | uspto-grants-2009_07 |