4-Fluorobenzaldehyde → HCID 178505538, compound

Participants

Reaction Conditions

Reaction Steps

A sealed tube containing 3,2′:3′,4″-terpyridine-5′,6′-diamine (Intermediate 2,148 mg, 0.56 mmol), 4-fluorobenzaldehyde (57.0 μL, 0.53 mmol) and dioxane (3 mL) was filled with air and heated to 100° C. for 6 days. Then, the solvent was removed and CH3CN (2 mL) followed by Yb(OTf)3 were added, and the reaction mixture was stirred for 4 days at room temperature. Afterwards, the solvent was evaporated in vacuo and the residue was purified by flash column chromatography (CH2Cl2/EtOH/aq NH3 100:8:1) to afford the title compound as a white solid (27 mg, 13%).

Provenance & Evidence