Hydrazine → HCID 178514333, compound

HRID 2264219Notes

Reaction equation

HRID 2264219 reaction equation
[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]1[CH:9]=[C:10]2[N:22]=[C:21](SC)[NH:20][C:11]2=[N:12][C:13]=1[C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1.[NH2:25][NH2:26]>>[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]1[CH:9]=[C:10]2[N:22]=[C:21]([NH:25][NH2:26])[NH:20][C:11]2=[N:12][C:13]=1[C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 9321HydrazineHCID 178503329HCID 178503329, compound

Product 1

HCID 178514333HCID 178514333, compound

Procedure

A solution of 6-(3-fluoropyridin-4-yl)-2-(methylthio)-5-pyridin-3-yl-3H-imidazo[4,5-b]pyridine (Example 47, 0.05 g, 0.15 mmol) in hydrazine (0.5 mL) was heated in a sealed tube at 100° C. for 30 hours. The solvent was evaporated and the residue (0.05 g) was used in the next step without further purification.

Workup

  1. customThe solvent was evaporated
  2. customthe residue (0.05 g) was used in the next step without further purification

Sources & evidence

ORD record
ord-4ffc9c8599bb4970a9ae022102b0fa63
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

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