2-(4-Aminophenoxy)ethanol → HCID 58692245, compound

Participants

Reaction Steps

Using the procedure of example 1, 2-(4-aminophenoxy)-ethanol (265 mg) was reacted with compound 1f (200 mg) to provide compound 4 (132 mg, 71%). 1H NMR (400 MHz, CD3OD) δ 8.85 (d, J=8.0 Hz, 1H), 8.25 (d, J=4.8 Hz, 1H), 8.23 (d, J=5.2 Hz, 1H), 8.22 (s, 1H), 7.54 (d, J=9.0 Hz, 2H), 7.18 (dd, J=8.0 Hz, 4.8 Hz, 1H), 7.16 (d, J=5.2 Hz, 1H), 6.98 (d, J=9.0 Hz, 2H). MS (ESI) m/z: 348 (M+H)+.

Provenance & Evidence