Cyclohexanemethylamine → HCID 11645208, compound

Participants

Reaction Steps

Using the procedure of example 1, C-cyclohexyl-methylamine (92 mg) was reacted with compound 1f (100 mg) to provide compound 16 (42 mg, 51%). 1H NMR (400 MHz, CD3OD) δ 8.96 (d, J=7.8 Hz, 1H), 8.28 (d, J=4.8 Hz, 1H), 8.20 (s, 1H), 8.12 (d, J=5.6 Hz, 1H), 7.25 (dd, J=7.8 Hz, 4.8 Hz, 1H), 7.02 (d, J=5.6 Hz, 1H), 3.37 (d, J=4.8 Hz, 2H), 1.94-1.90 (m, 5H), 1.34-1.04 (m, 6H). MS (ESI) m/z: 308 (M+H)+.

Provenance & Evidence