4-Bromo-2-methylaniline → HCID 58692204, compound

Participants

Reaction Steps

Using the procedure of example 1, 4-bromo-2-methylaniline (300 mg) was reacted with compound 1f (200 mg) to provide compound 41 (85 mg, 41%). 1H NMR (400 MHz, DMSO) δ 12.28 (br s, 1H), 8.75 (br s, 1H), 8.55 (d, J=7.8 Hz, 1H), 8.43 (s, 1H), 8.28 (d, J=7.2 Hz, 1H), 8.26 (m, 1H), 7.52 (m, 2H), 7.40 (d, J=10.8 Hz, 1H), 7.27 (d, J=7.2 Hz, 1H), 7.06 (dd, J=10.8 Hz, 6.0 Hz, 1H), 2.25 (s, 3H).

Provenance & Evidence