Sodium Hydroxide → HCID 23112207, compound

HRID 2264326Notes

Reaction equation

HRID 2264326 reaction equation
[Cl:1][C:2]1[C:11]2[O:10][CH2:9][C:8](=[O:12])[NH:7][C:6]=2[CH:5]=[C:4]([NH:13]C(=O)C(F)(F)F)[CH:3]=1.[OH-].[Na+]>>[NH2:13][C:4]1[CH:3]=[C:2]([Cl:1])[C:11]2[O:10][CH2:9][C:8](=[O:12])[NH:7][C:6]=2[CH:5]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23112210HCID 23112210, compound

Product 1

HCID 23112207HCID 23112207, compound

Procedure

N-(8-Chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-2,2,2-trifluoroacetamide was hydrolyzed with sodium hydroxide to obtain 6-amino-8-chloro-2H-1,4-benzoxazin-3(4H)-one.

Sources & evidence

ORD record
ord-977854c8d68f4cc8a243ba11a25601fc
Source dataset
uspto-grants-2010_12
Patent number
US07855198B2

Reaction notes

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