HCID 57837615, compound → HCID 23112254, compound

HRID 2264329Notes

Reaction equation

HRID 2264329 reaction equation
C([O:8][C:9](=O)[CH:10]([C:21]1[C:26]([C:27]([F:30])([F:29])[F:28])=[CH:25][C:24]([N+:31]([O-])=O)=[CH:23][C:22]=1[N+:34]([O-])=O)C(OCC1C=CC=CC=1)=O)C1C=CC=CC=1>[Pd].C(O)C>[NH2:31][C:24]1[CH:23]=[C:22]2[C:21]([CH2:10][C:9](=[O:8])[NH:34]2)=[C:26]([C:27]([F:30])([F:29])[F:28])[CH:25]=1

Participants

4

Reactant 1

HCID 57837615HCID 57837615, compound

Product 1

HCID 23112254HCID 23112254, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Palladium/carbon was added to an ethanol solution of [2,4-dinitro-6-(trifluoromethyl)phenyl]malonic acid dibenzyl ester and the reaction was carried out under a hydrogen atmosphere to obtain 6-amino-4-(trifluoromethyl)-1,3-dihydro-2H-indol-2-one.

Sources & evidence

ORD record
ord-7161835b7bf2410fa5e6a715da3b4414
Source dataset
uspto-grants-2010_12
Patent number
US07855198B2

Reaction notes

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