Hydrochloric Acid → HCID 68781035, compound

Participants

Reaction Steps

A solution of 2-(1-tert-butoxycarbonyl-piperidin-4-ylamino)-pyrimidine-5-carboxylic acid (0.18 g, 0.56 mmol) in ethanol (5 mL) and 4 M HCl in dioxane (10 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 223.3 [M+H]+.

Provenance & Evidence