Hydrochloric Acid → HCID 68781850, compound

Participants

Reaction Steps

A solution of 4-(5,5,7,7-tetramethyl-5,7-dihydro-furo[3,4-d]pyrimidin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.23 g, 3.27 mmol) in 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 277.3 [M+H]+.

Provenance & Evidence